Publications

Molecular Targets of Triple-Negative Breast Cancer: Where Do We Stand? Newton EE, Mueller LE, Treadwell SM, Morris CA, Machado HL. Cancers. 2022; 14: 482.

FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis.

Iftikhar R, Penrose HM, King AN, Kim Y, Ruiz E, Kandil E, Machado HL, Savkovic SD. Metabolites. 2022; 12.


Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. Ibrahim AM, Moss MA, Gray Z, Rojo MD, Burke CM, Schwertfeger KL, Dos Santos CO, Machado HL. Front Oncol. 2020;10:569985.


Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice. Wang Y, Chaffee TS, LaRue RS, Huggins DN, Witschen PM, Ibrahim AM, Nelson AC, Machado HL, Schwertfeger KL. Elife. 2020;9.


Gas6 expression is reduced in advanced breast cancers. Ibrahim AM, Gray Z, Gomes AM, Myers L, Behbod F, Machado HL. NPJ precision oncology. 2020;4:9.


Gas6 is dispensable for pubertal mammary gland development. Mills KL, Gomes AM, Standlee CR, Rojo MD, Carmeliet P, Lin Z, Machado HL. PLoS One. 2018;13(12):e0208550.


Stromal Gas6 promotes the progression of premalignant mammary cells. Gomes AM, Carron EC, Mills KL, Dow AM, Gray Z, Fecca CR, Lakey MA, Carmeliet P, Kittrell F, Medina D, Machado HL. Oncogene. 2019;38(14):2437-2450.


Breaking through to the Other Side: Microenvironment Contributions to DCIS Initiation and Progression. Nelson AC, Machado HL, Schwertfeger KL. J Mammary Gland Biol Neoplasia. 2018;23(4):207-221.


Modeling Human Ductal Carcinoma In Situ in the Mouse. Behbod F, Gomes AM, Machado HL. Journal of mammary gland biology and neoplasia. 2018;23(4):269-278.


Macrophages promote the progression of premalignant mammary lesions to invasive cancer. Carron EC, Homra S, Rosenberg J, Coffelt SB, Kittrell F, Zhang Y, Creighton CJ, Fuqua SA, Medina D, Machado HL. Oncotarget. 2017;8(31):50731-50746.


A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bullet. D'Errico G, Machado HL, Sainz B, Jr. Clin Transl Med. 2017;6(1):3.


Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies. Sainz B, Jr., Carron E, Vallespinos M, Machado HL. Mediators Inflamm.  2016;2016:9012369.